© 2006 American Thoracic Society
Noninvasive Ventilation versus Nonrebreather BagValve Mask to Achieve Preoxygenation before Intubation of Hypoxic PatientsFrom the Authors:We thank Drs. Lopera and Quintana for their comments on our recent article (1), which help us to clarify the description of our method of oxygen delivery. Indeed, they correctly point out that preoxygenation effectiveness depends on the FIO2 delivery methodology, which in turn depends on whether an oxygen reservoir is added or not to the balloon (2). In our study, we used a balloon with an oxygen reservoir bag, which allowed us to deliver high FIO2, a system widely used in the intensive care units (3). This information is helpful in interpreting the study's conclusions. The significant improvement in oxygenation observed after 3 min of preoxygenation using noninvasive ventilation (NIV) is probably due to the recruitment of collapsed alveoli rather than a higher delivered oxygen concentration (1, 4). It is also important to notice that the beneficial effect on PaO2 was still observed 30 min after endotracheal intubation in patients receiving NIV during preoxygenation. One explanation could be again the effect of NIV in recruiting alveoli and increasing lung volume prior to intubation.
Avicenne Hospital Paris 13 UniversityAP-HP, EA 3409 Bobigny, France
University Hospital of Montpellie and Saint Eloi Hospital, Montpellier University, Montpellier, France FOOTNOTES Conflict of Interest Statement: Neither author has a financial relationship with a commercial entity that has an interest in the subject of this manuscript. REFERENCES
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