help button home button
AJRCCM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by CHATILA, W.
Right arrow Articles by CRINER, G. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by CHATILA, W.
Right arrow Articles by CRINER, G. J.

Am. J. Respir. Crit. Care Med., Volume 162, Number 4, October 2000, 1292-1296

Acute Respiratory Failure after Lung Volume Reduction Surgery

WISSAM CHATILA, SATOSHI FURUKAWA, and GERARD J. CRINER

Division of Pulmonary and Critical Care Medicine, Department of Medicine, and Cardiothoracic Division, Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania

In this study, we characterized patients who developed respiratory failure postoperatively after lung volume reduction surgery (LVRS). We retrospectively reviewed the records of 72 patients who underwent LVRS from February 1995 to February 1998, examining perioperative variables and complications. Twenty-one patients (29%) developed postoperative respiratory failure, five due to hypoxemia, nine due to hypercapnia, and seven secondary to hemodynamic instability. The hospital mortality was 33% among patients who developed respiratory failure. No preoperative clinical or physiologic variable (including percent ideal body weight, serum albumin, prednisone use, lung function, maximal O2 uptake on exercise testing, 6-min walk distance, and hemodynamic parameters) was predictive of postoperative respiratory failure. Patients who developed respiratory failure were older (63 ± 7 versus 57 ± 8 yr, p = 0.01), had longer anesthesia time (188 ± 96 versus 127 ± 56 min, p = 0.001), had a higher incidence of coronary artery disease (40% versus 10%, p = 0.001) and performance of concomitant surgical procedures during the LVRS operation (40% versus 2%, p < 0.001) compared with those without respiratory failure. All patients who underwent simultaneous surgery, which were mostly for cardiac disease, developed respiratory failure. Risk factor analysis confirmed that older patients and those undergoing cardiac surgery combined with LVRS are at increased risk for postoperative respiratory failure.




This article has been cited by other articles:


Home page
 Proc Am Thorac SocHome page
N. W. Brister, R. E. Barnette, V. Kim, and M. Keresztury
Anesthetic Considerations in Candidates for Lung Volume Reduction Surgery
Proceedings of the ATS, May 1, 2008; 5(4): 432 - 437.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
M. J. TOBIN
Chronic Obstructive Pulmonary Disease, Pollution, Pulmonary Vascular Disease, Transplantation, Pleural Disease, and Lung Cancer in AJRCCM 2000
Am. J. Respir. Crit. Care Med., November 15, 2001; 164(10): 1789 - 1804.
[Full Text] [PDF]

Home page
 NEJMHome page
National Emphysema Treatment Trial Research Group
Patients at High Risk of Death after Lung-Volume-Reduction Surgery
N. Engl. J. Med., October 11, 2001; 345(15): 1075 - 1083.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Proc. Am. Thorac. Soc. Am. J. Respir. Cell Mol. Biol.
Copyright © 2000 American Thoracic Society 		  ATS State of the Art 2009