The American-European Consensus Conference on ARDS, Part 2 . Ventilatory, Pharmacologic, Supportive Therapy, Study Design Strategies, and Issues Related to Recovery and Remodeling

The American-European Consensus Conference on ARDS, Part 2
Ventilatory, Pharmacologic, Supportive Therapy, Study Design Strategies, and Issues Related to Recovery and Remodeling

ANTONIO ARTIGAS, GORDON R. BERNARD, JEAN CARLET, DIDIER DREYFUSS, LUCIANO GATTINONI, LEONARD HUDSON, MAURICE LAMY, JOHN J. MARINI, MICHAEL A. MATTHAY, MICHAEL R. PINSKY, ROGER SPRAGG, PETER M. SUTER, and the Consensus Committee

The acute respiratory distress syndrome (ARDS) continues as a contributor to the morbidity and mortality of patients in intensivecare units throughout the world, imparting tremendous human andfinancial costs. During the last 10 years there has been a declinein ARDS mortality without a clear explanation. The American-EuropeanConsensus Committee on ARDS was formed to re-evaluate the standardsfor the ICU care of patients with acute lung injury (ALI), withregard to ventilatory strategies, the more promising pharmacologicagents, and the definition and quantification of pathologic featuresof ALI that require resolution. It was felt that the definitionof strategies for the clinical design and coordination of studiesbetween centers and continents was becoming increasingly importantto facilitate the study of various new therapies for ARDS.

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